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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0430c7ede18031b7a9b4552246a2b226c2219fa758dd33364e8d26a190388dd' 
  AND token = 'P4aGvkCIGeXr69S/Gi92HirykPEwNzmZydK91qJTdIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}