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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e385ea373e00d2a187acbffe89606a7e79f433ebb98bff4fe68c8753de93fd0' 
  AND token = 'e8QmxOPQXxxlWWPMhEmRSvv4JbUk6O4u8+1XH0WL40g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}