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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d981a5404028602ae3c897f45c9c2ce98cd767a28ecf3d045d27e4b8c23f05d' 
  AND token = 'QkUWQaezxcfZNmXuvnH7CcMKenOrMQIqpJ75i1ZOR3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}