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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd10da0b3b3253f6eb0d95b3fbf41cced8cd11493e445a391e8542320905c6e' 
  AND token = 'sPyScqOJvy5tn78aLlPXGQxKIncEJ6EC6L9HCSuH0+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}