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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd12e65bddb122b5c49bce456cc2763e4c78127f5818210edd46d8d93b56f9e66' 
  AND token = 'q1pu5vKQcC+ZgSP8Q9sx60xlLg07C9FGH1ryIHEHVbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}