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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f333c5f2bf69101f6fa225c7d97763aa55f70013aa4059b60b4c69e563702ec2' 
  AND token = 'ta1GN42O/l1/E8JVJDWiVHvaTygdrHfEgeY3GN9XwA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}