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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d1445f52ace1aab1c9a916fd3f8603b8a6e2489a85a33ed564d35a2c19c28d' 
  AND token = 'u+XT+3nYfY0vdCoDWnDMuwA7qX0NP3epNJ+hTVmuPXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}