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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222e4ee77d1a0cb591486366d7929af32e9b99a9eba3514f09f7fe2e15579f27' 
  AND token = 'TZ0fiNm0mUX8V2YSTRjZVRYjoYsbCSv75lCt7ZQK6ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}