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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e68a009e32fcdcea0ffb2a12577d8ece5d7a5b35319025efcd55b9dc31d8e3' 
  AND token = 'KF32KteIjq/rBqlSpcS8HGdW/JyX+lMpktAbWo1j7Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}