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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e338cd64fe2c7505559a60b66dd28b98a638294cd08c921b3f8fbf39ee4a9d10' 
  AND token = '8xkotUXYDbG0BCaBXKi1DHmRBPVd1hzBheZqXd7fZb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}