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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c05e4740ded74425bd7edb51b0e8674ae627d48284dbc9cbc46251220a00582' 
  AND token = 'jxPxI5KWGx/Ds9g4eD20c2H/Ao7BnrUpZHkhD+NtkN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}