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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18343f41fdcf6d4a6c24579fec5b164cc00263c810675d5e3ee88b96f28c624a' 
  AND token = 'jmuJB0/yVKhF+3VLi+ik2Y0IiZA6Q5yqNmvcdokSEvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}