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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bff0494b6c962829d2f3388c767825db3818d13f844681945adc020f2a4fd9c' 
  AND token = '0V5CRLR5jEZfSWVn1GsmL3+g5mQMtRTOOjRTMOUnYU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}