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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7fc0c9e6d16d5b5d1bc991a52e495a116b6d93d202873cc12b88e5c52b207f' 
  AND token = 'rnkCfFH+RCdGAaEjvKpkvW7mlo8IJAJ4f+nUehOb8Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}