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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '137233a2e4234c33b65acec73a708064d4b78b7aafe141538eb390965b4e230a' 
  AND token = 'vM9StPC0FRuRBmME/YnvYwqSw62jtjldm4saMmp9u0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}