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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ad1fe6c34825113a8430c38edb4fb6ff60ece403e0fdd007cc12694851f917' 
  AND token = 'HUUNjTXBTVIX9IOdB2SinXdhmGzWWdm0joZAUNP8yzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}