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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ae17f89de6df8936234f5c6ad6a0349c8ce819901c70fc0b60229b8b7b73e4' 
  AND token = 'dubKteRdP3nAS8HL3AFAib9Zuem1+ZhUbqXgtfH9B9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}