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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8006b809c0a0d7b9a31e07dfa7f6318627f14657a65906adcb56fa0537343f52' 
  AND token = 'uUXb6klOEUyTNgildVmbicoQE0rOY9UK1yKVug6KWN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}