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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372078e2af00ba3cc4de2e1d2449eda746ec86dc3beaef74133280e9d6da6736' 
  AND token = '8j/pBl6fL8PS1u5o3ZkLfKKevuYwf0rxnE8n5evR6ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}