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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d8ad1a7ece3fe5def28b33a943c77aa7544ba5066abd5af58019ff21c55ef1' 
  AND token = 'T2RBtvZAlUhfRyjAH9Dk5akBWY20pSiCmVNysyTakC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}