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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eefafcb18eea216da6fec07464b7106c76c6d5dcb4511fc3a7d19ac4bbe8c078' 
  AND token = 'X1D78iWCzmxEaY1tm01BrKK0AfE6P/NOKkhMnk0jU/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}