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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edb1817bb92c87777a9c259cd2f95652b0908879e7f0bd65777a99c1b1bee35' 
  AND token = 'Vibcd0ACT4nqg4+oNN0NCVnggaVPLgkudEdzHXmEtGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}