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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a18a923cab0d49c6a54a6be9f6001a22874a3b8c2b1945661bb52b5b7ea31ee' 
  AND token = 'LtZNHqc3Tu0jb2am7CJYq3j3KxXjz4vjwaTlvfz2c98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}