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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd851c9ee678a9225827200338f7c3632ef5814b2dcc279a2c72160beec3d8307' 
  AND token = 'FlVCPXbL3Q4Pyty+JOnhdmZhuvESNhD2btRcQvGsxuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}