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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e652ea41bf279c93beb3e271e191641fc9458ab070dfcfe1ac148658fcbcf6' 
  AND token = 'Fj9LRZIqQJ0CTCC6u8kOUPfnFTm0nS1ykJTCbbpY4yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}