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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8cef45c6003844227a4d26535a1f88314674e805711e43a281fc02674b4721' 
  AND token = 'C0MEylLTn6WWZ+U7gkUVlJibrIAHX35RMuasOGaf63g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}