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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e5a64d7627c159d92b8a3f62c57ca48e67ddb7de9ae650c6753debf1590b7e' 
  AND token = 'z9ivaiMWoHsORZyep5tnaUce604l6XQv7e0OcNvLQMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}