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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740ab3d4a859cf9b82ff6bfece6308a6f2afe073c803ab6073d73b7130229043' 
  AND token = 'UOLrHUGZj/pDQ+FT9LbZU7pbeT69tfSZTN/8aC4ro30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}