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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df54fee318b70554cbed052f8a7d1efe16f12f378469b5a9ea65cf298b5d6f10' 
  AND token = 'alqOI5HzoSt1estd8JEm0AjfogQTgvskPj36hEdbnDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}