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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df5e71c63c99fe465f3607e95d0a2f9ab74d99ea4612d2f201107c9717aa1b0' 
  AND token = 'C6VkvRP/cM5XVzV2fsk3i45PYhsRmhrK8H5kLKmdOlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}