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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b24edc2b6766299ff1f0eb83e075f4fced24bb4cd943d5c0a3e4362589de100' 
  AND token = 'Ts7OHRPABZh5ZcmxAvNDiviZ4mtoTDlac98Vo1OiGGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}