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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecf95e1fd4988ce307750af96be6cf2eea64155e81f7ee65510fada7bc6ee954' 
  AND token = '+hokecsYGYG0VZZ6nZB/rFCqRH0bLHuJeFRy56GSBKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}