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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d24cee4d5c84dc5c0432aece2178abcc0d30a1f07454fd1cd1b98edb05ca0e' 
  AND token = 'S+zsWTwHlV6l6hAQn7r42Skh6AnGlo7W16XOcWjZy5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}