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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7953e4231d2ab7c1916060e20fe29f5e3714ae3b2a5d809cb7f700e02cda3d' 
  AND token = 'dzu6NN24VHG/RTwQ8GtE+6aGoEn/bq49kVIKHcOtexA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}