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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff798903f1e0149198cb27d154f7750e3826e4aceca6a73d7f3c9eb0f0d3431' 
  AND token = '0sv54LFTmpGJckTVNi3A50LrjRucdfWbeNXQLiZzCbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}