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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3805c226695964987373fb51267d9cc0cb924742c4b4d879203108c0e6674e' 
  AND token = '9PIWUHr4FIaLc/AyqT+p1s2qO55HZ4cOB0T3NGbW1SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}