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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '414ade2eab1f0435805506485a45726e7a4c4475ae62140654ac0000f458118b' 
  AND token = 'Icg586QHpXU9CsaTgAYOqCtd4b8A8+wAVzrnmBbFHLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}