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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '584fe4621e7b4e2c24f4fd4ca8c4914bcff3e49277679c2774025f347f798076' 
  AND token = 'uphOKLp+Lc1ZdhN7v4UKvLIJ+h1yBCyIX+dtEc9scMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}