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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db1901e78554b2f81c3b2224c86b76b3505d2ace6e7be84b1e704b4baa843578' 
  AND token = '3Izi+kYlGDgc0iNB1SM34hbQthPgSPfLbWIvDl+VYX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}