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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f749ff909fca528d347d1c3ccb51db01bf5bde3095683e12a1fb4273a0682111' 
  AND token = 'wEm86nzqJ7NCFFj4gtknxrgsM9I2kp9tyFfPrS0dFMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}