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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c35b3ba7c590d96ed9706b1201be8968405f14175c7d2424101e2dc868af8e2' 
  AND token = 'aSFo78y4wr9F/wrLJJxcftXbGJ58Dr3wbW2wU0Daa8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}