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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d40b6665113a6c1aff201f8a8d450b827180ce48068817efa71b0077645502' 
  AND token = 'Se3WWQQE+s4rtQpl8bia1veS796YcX40w2ZG/EqnSE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}