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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fc7690489571995e5a01692b453bbf9960df47fd8e48a3a5a0293dcface56d' 
  AND token = 'UQC2klKKAXdWrtRiaR4xvEUZ7UQur6NqO53B0Sn+s0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}