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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d62e90a56fb687a5c6cbbe5b032a27017518349cd09faf902d4f4a7534abaf' 
  AND token = 'fIKSpWEiJctcE9oop0UhXVwfVmlRJVUG3B5R49Uss50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}