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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678c9a7f4af04aeefc141aa5422e9c33975894d3be76b20bb60b5e2532090785' 
  AND token = '2xMxKJka3Dp8PRQThXCIqMkLzlhrWK7/3OJvJiSeP1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}