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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '569ef43f8ef1be028387959d9e7a7c06791cafadcd4d24f43e3dd65c703d6438' 
  AND token = 'UcF75lg7M9Gth8Gn/4Jc69smpGDWegbBe0mlrrQ4d+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}