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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f89456433bd7231c3d60c23e82fe258447add285f181a50fa0dae2ab129cc43' 
  AND token = 'rXpXeKUvZOXNAaxQSApMC131+z14gVEh0gMCHLoMeRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}