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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e54685dab2251347675918660e3fbd41b227e2b7d9263678d688f5fde382ae6' 
  AND token = 'ODVAei0OsfHqSgFZgZBsl6BNIK+uA3ve1JwsEuFncSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}