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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51ce0979393e123e90106f80e23a47b20601ffc7e77d631086f5a7a02f1cd72' 
  AND token = 'TVdRI1YGV+EpAUIcH8Ph/Ydy4TKFcpuuOSQ9PWiJPZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}