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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f45a61a36e9f802e3b90c0bc4cc88ea2a5c6dc456e14c0634eeed247882412b' 
  AND token = 'meSpsueqHp5232XCiUB8eiDgtjIgqCrVgU36laTHvAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}